1jt6
From Proteopedia
(Difference between revisions)
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<StructureSection load='1jt6' size='340' side='right'caption='[[1jt6]], [[Resolution|resolution]] 2.54Å' scene=''> | <StructureSection load='1jt6' size='340' side='right'caption='[[1jt6]], [[Resolution|resolution]] 2.54Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1jt6]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1jt6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JT6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JT6 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DEQ:DEQUALINIUM'>DEQ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DEQ:DEQUALINIUM'>DEQ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1jt0|1jt0]], [[1jty|1jty]], [[1jum|1jum]], [[1jup|1jup]], [[1jus|1jus]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1jt0|1jt0]], [[1jty|1jty]], [[1jum|1jum]], [[1jup|1jup]], [[1jus|1jus]]</div></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jt6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jt6 OCA], [https://pdbe.org/1jt6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jt6 RCSB], [https://www.ebi.ac.uk/pdbsum/1jt6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jt6 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/QACR_STAAU QACR_STAAU]] Transcriptional repressor of qacA. Binds to IR1, an unusually long 28 bp operator, which is located downstream from the qacA promoter and overlaps its transcription start site. QacR is induced from its IR1 site by binding to one of many structurally dissimilar cationic lipophilic compounds, which are also substrates of QacA. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 06:45, 11 August 2021
Crystal structure of the multidrug binding protein QacR bound to dequalinium
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