6xcy

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==Porcine pepsin in complex with ritonavir==
==Porcine pepsin in complex with ritonavir==
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<StructureSection load='6xcy' size='340' side='right'caption='[[6xcy]]' scene=''>
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<StructureSection load='6xcy' size='340' side='right'caption='[[6xcy]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6XCY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6XCY FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6xcy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6XCY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6XCY FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6xcy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6xcy OCA], [https://pdbe.org/6xcy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6xcy RCSB], [https://www.ebi.ac.uk/pdbsum/6xcy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6xcy ProSAT]</span></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=RIT:RITONAVIR'>RIT</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Pepsin_A Pepsin A], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.1 3.4.23.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6xcy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6xcy OCA], [https://pdbe.org/6xcy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6xcy RCSB], [https://www.ebi.ac.uk/pdbsum/6xcy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6xcy ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[[https://www.uniprot.org/uniprot/PEPA_PIG PEPA_PIG]] Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Silvaggi NR]]
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[[Category: Pepsin A]]
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[[Category: Vuksanovic N]]
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[[Category: Sus scrofa]]
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[[Category: Silvaggi, N R]]
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[[Category: Vuksanovic, N]]
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[[Category: Complex]]
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[[Category: Hiv]]
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[[Category: Hydrolase]]
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[[Category: Hydrolase-inhibitor complex]]
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[[Category: Inhibitor]]
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[[Category: Pepsin]]

Revision as of 06:14, 18 August 2021

Porcine pepsin in complex with ritonavir

PDB ID 6xcy

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