1lqq

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<StructureSection load='1lqq' size='340' side='right'caption='[[1lqq]], [[NMR_Ensembles_of_Models | 15 NMR models]]' scene=''>
<StructureSection load='1lqq' size='340' side='right'caption='[[1lqq]], [[NMR_Ensembles_of_Models | 15 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1lqq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Leiurus_quinquestriatus_quinquestriatus Leiurus quinquestriatus quinquestriatus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LQQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1LQQ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1lqq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Leiurus_quinquestriatus_quinquestriatus Leiurus quinquestriatus quinquestriatus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LQQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LQQ FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1lqq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lqq OCA], [http://pdbe.org/1lqq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1lqq RCSB], [http://www.ebi.ac.uk/pdbsum/1lqq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1lqq ProSAT]</span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lqq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lqq OCA], [https://pdbe.org/1lqq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lqq RCSB], [https://www.ebi.ac.uk/pdbsum/1lqq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lqq ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SCX3_LEIQU SCX3_LEIQU]] Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission. This contractive toxin is highly toxic both to mammals and insects.
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[[https://www.uniprot.org/uniprot/SCX3_LEIQU SCX3_LEIQU]] Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission. This contractive toxin is highly toxic both to mammals and insects.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 06:48, 18 August 2021

ANTI-MAMMAL AND ANTI-INSECT LQQIII SCORPION TOXIN, NMR, 15 STRUCTURES

PDB ID 1lqq

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