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7p5j
From Proteopedia
(Difference between revisions)
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==Cryo-EM structure of human TTYH1 in GDN== | ==Cryo-EM structure of human TTYH1 in GDN== | ||
| - | <StructureSection load='7p5j' size='340' side='right'caption='[[7p5j]]' scene=''> | + | <StructureSection load='7p5j' size='340' side='right'caption='[[7p5j]], [[Resolution|resolution]] 4.00Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7P5J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7P5J FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7p5j]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7P5J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7P5J FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p5j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p5j OCA], [https://pdbe.org/7p5j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p5j RCSB], [https://www.ebi.ac.uk/pdbsum/7p5j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p5j ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> |
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TTYH1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p5j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p5j OCA], [https://pdbe.org/7p5j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p5j RCSB], [https://www.ebi.ac.uk/pdbsum/7p5j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p5j ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/TTYH1_HUMAN TTYH1_HUMAN]] Probable chloride channel. May be involved in cell adhesion (By similarity). Isoform 3 may be a Ca(2+)-independent and swelling-activated chloride channel, possibly involved in regulation of cell volume. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Deneka D]] | + | [[Category: Deneka, D]] |
| - | [[Category: Dutzler R]] | + | [[Category: Dutzler, R]] |
| - | [[Category: Sawicka M]] | + | [[Category: Sawicka, M]] |
| - | [[Category: Straub | + | [[Category: Straub, M S]] |
| - | [[Category: Sukalskaia A]] | + | [[Category: Sukalskaia, A]] |
| + | [[Category: Lipid metabolism]] | ||
| + | [[Category: Lipid transport]] | ||
| + | [[Category: Membrane protein]] | ||
Revision as of 06:38, 25 August 2021
Cryo-EM structure of human TTYH1 in GDN
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