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7rrp
From Proteopedia
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==Apoferritin structure at 1.27 angstrom resolution determined from a 300 kV Titan Krios G3i electron microscope with Falcon4 detector== | ==Apoferritin structure at 1.27 angstrom resolution determined from a 300 kV Titan Krios G3i electron microscope with Falcon4 detector== | ||
| - | <StructureSection load='7rrp' size='340' side='right'caption='[[7rrp]]' scene=''> | + | <StructureSection load='7rrp' size='340' side='right'caption='[[7rrp]], [[Resolution|resolution]] 1.27Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RRP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RRP FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7rrp]] is a 24 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RRP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RRP FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7rrp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7rrp OCA], [https://pdbe.org/7rrp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7rrp RCSB], [https://www.ebi.ac.uk/pdbsum/7rrp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7rrp ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[7k3w|7k3w]]</div></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FTH1, FTH, FTHL6, OK/SW-cl.84, PIG15 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Ferroxidase Ferroxidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.16.3.1 1.16.3.1] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7rrp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7rrp OCA], [https://pdbe.org/7rrp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7rrp RCSB], [https://www.ebi.ac.uk/pdbsum/7rrp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7rrp ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/FRIH_HUMAN FRIH_HUMAN]] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity). | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Ferroxidase]] | ||
| + | [[Category: Human]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Chiu W]] | + | [[Category: Chiu, W]] |
| - | [[Category: Pintilie G]] | + | [[Category: Pintilie, G]] |
| - | [[Category: Zhang K]] | + | [[Category: Zhang, K]] |
| + | [[Category: Apoferritin]] | ||
| + | [[Category: Atomic resolution]] | ||
| + | [[Category: Cryo-em]] | ||
| + | [[Category: Falcon4 detector]] | ||
| + | [[Category: Oxidoreductase]] | ||
Revision as of 06:40, 25 August 2021
Apoferritin structure at 1.27 angstrom resolution determined from a 300 kV Titan Krios G3i electron microscope with Falcon4 detector
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