This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
7rrp
From Proteopedia
(Difference between revisions)
m (Protected "7rrp" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
==Apoferritin structure at 1.27 angstrom resolution determined from a 300 kV Titan Krios G3i electron microscope with Falcon4 detector== | ==Apoferritin structure at 1.27 angstrom resolution determined from a 300 kV Titan Krios G3i electron microscope with Falcon4 detector== | ||
| - | <StructureSection load='7rrp' size='340' side='right'caption='[[7rrp]]' scene=''> | + | <StructureSection load='7rrp' size='340' side='right'caption='[[7rrp]], [[Resolution|resolution]] 1.27Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RRP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RRP FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7rrp]] is a 24 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RRP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RRP FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7rrp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7rrp OCA], [https://pdbe.org/7rrp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7rrp RCSB], [https://www.ebi.ac.uk/pdbsum/7rrp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7rrp ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[7k3w|7k3w]]</div></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FTH1, FTH, FTHL6, OK/SW-cl.84, PIG15 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Ferroxidase Ferroxidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.16.3.1 1.16.3.1] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7rrp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7rrp OCA], [https://pdbe.org/7rrp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7rrp RCSB], [https://www.ebi.ac.uk/pdbsum/7rrp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7rrp ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/FRIH_HUMAN FRIH_HUMAN]] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity). | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Ferroxidase]] | ||
| + | [[Category: Human]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Chiu W]] | + | [[Category: Chiu, W]] |
| - | [[Category: Pintilie G]] | + | [[Category: Pintilie, G]] |
| - | [[Category: Zhang K]] | + | [[Category: Zhang, K]] |
| + | [[Category: Apoferritin]] | ||
| + | [[Category: Atomic resolution]] | ||
| + | [[Category: Cryo-em]] | ||
| + | [[Category: Falcon4 detector]] | ||
| + | [[Category: Oxidoreductase]] | ||
Current revision
Apoferritin structure at 1.27 angstrom resolution determined from a 300 kV Titan Krios G3i electron microscope with Falcon4 detector
| |||||||||||
