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1nfj

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<StructureSection load='1nfj' size='340' side='right'caption='[[1nfj]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='1nfj' size='340' side='right'caption='[[1nfj]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1nfj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arcfl Arcfl]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NFJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NFJ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1nfj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arcfl Arcfl]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NFJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NFJ FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1nfh|1nfh]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1nfh|1nfh]]</div></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nfj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nfj OCA], [http://pdbe.org/1nfj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1nfj RCSB], [http://www.ebi.ac.uk/pdbsum/1nfj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1nfj ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nfj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nfj OCA], [https://pdbe.org/1nfj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nfj RCSB], [https://www.ebi.ac.uk/pdbsum/1nfj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nfj ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ALBA2_ARCFU ALBA2_ARCFU]] Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes (By similarity).[HAMAP-Rule:MF_01122]
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[[https://www.uniprot.org/uniprot/ALBA2_ARCFU ALBA2_ARCFU]] Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes (By similarity).[HAMAP-Rule:MF_01122]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 07:02, 25 August 2021

Structure of a Sir2 substrate, alba, reveals a mechanism for deactylation-induced enhancement of DNA-binding

PDB ID 1nfj

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