This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Histone acetyltransferase 3D structures
From Proteopedia
(Difference between revisions)
| Line 4: | Line 4: | ||
{{#tree:id=OrganizedByTopic|openlevels=0| | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
| - | *Histone acetyltransferase; Human domains – HAT 170-458; catalytic 497-662; bromodomain 729-837; | + | *Histone acetyltransferase; Human domains – DPF 194-323; HAT 170-458; catalytic 497-662; bromodomain 729-837; |
**[[1f68]] – hHAT bromodomain (mutant) – human – NMR | **[[1f68]] – hHAT bromodomain (mutant) – human – NMR | ||
| Line 29: | Line 29: | ||
**[[7cmr]] - hHAT KAT8 1-458 <br /> | **[[7cmr]] - hHAT KAT8 1-458 <br /> | ||
**[[5j8c]], [[5j8f]] - hHAT KAT8 HAT domain (mutant)<br /> | **[[5j8c]], [[5j8f]] - hHAT KAT8 HAT domain (mutant)<br /> | ||
| + | **[[7by1]] - mHAT KAT2A N-terminal 67-378 - mouse<br /> | ||
**[[1qso]] - yHAT HPA2 – yeast<br /> | **[[1qso]] - yHAT HPA2 – yeast<br /> | ||
**[[3to7]] – yHAT Esa1<br /> | **[[3to7]] – yHAT Esa1<br /> | ||
| Line 38: | Line 39: | ||
**[[6ia8]], [[6iad]], [[6iaz]] - HAT – ''Methanocaldococcus infernus''<br /> | **[[6ia8]], [[6iad]], [[6iaz]] - HAT – ''Methanocaldococcus infernus''<br /> | ||
**[[6if4]] - HAT – ''Trypanosoma brucei''<br /> | **[[6if4]] - HAT – ''Trypanosoma brucei''<br /> | ||
| + | **[[7bwz]], [[7bx0]], [[7bx1]], [[7bxw]], [[7c3o]] - HAT RTT109 – ''Candida albicans''<br /> | ||
*Histone acetyltransferase binary complexes | *Histone acetyltransferase binary complexes | ||
| Line 56: | Line 58: | ||
**[[5lvq]], [[5lvr]], [[5fdz]], [[5fe0]], [[5fe1]], [[5fe2]], [[5fe3]], [[5fe4]], [[5fe5]], [[5fe6]], [[5fe7]], [[5fe8]], [[5fe9]], [[5mkx]] - hHAT KAT2B bromodomain + inhibitor<br /> | **[[5lvq]], [[5lvr]], [[5fdz]], [[5fe0]], [[5fe1]], [[5fe2]], [[5fe3]], [[5fe4]], [[5fe5]], [[5fe6]], [[5fe7]], [[5fe8]], [[5fe9]], [[5mkx]] - hHAT KAT2B bromodomain + inhibitor<br /> | ||
**[[4dnc]] – hHAT KAT8 HAT domain + male-specific lethal 1 homolog<br /> | **[[4dnc]] – hHAT KAT8 HAT domain + male-specific lethal 1 homolog<br /> | ||
| - | **[[3v43]], [[4lk9]], [[4lka]], [[4llb]], [[5b75]], [[5b76]], [[5b77]], [[5b78]] - hHAT KAT6A + H3.1 peptide<br /> | + | **[[3v43]], [[4lk9]], [[4lka]], [[4llb]], [[5b75]], [[5b76]], [[5b77]], [[5b78]], [[6lsb]] - hHAT KAT6A + H3.1 peptide<br /> |
**[[5u2j]], [[6oie]] - hHAT KAT6B + H3K14BU peptide<br /> | **[[5u2j]], [[6oie]] - hHAT KAT6B + H3K14BU peptide<br /> | ||
| - | **[[5gk9]], [[6maj]], [[6mak]] - hHAT KAT7 + BRD1<br /> | + | **[[5gk9]], [[6maj]], [[6mak]], [[7d0o]] - hHAT KAT7 + BRD1<br /> |
**[[4dnc]] – hHAT KAT8 HAT domain + male-specific lethal 1 homolog<br /> | **[[4dnc]] – hHAT KAT8 HAT domain + male-specific lethal 1 homolog<br /> | ||
**[[6ct2]], [[6ba2]] – hHAT KAT8 HAT domain + inhibitor<br /> | **[[6ct2]], [[6ba2]] – hHAT KAT8 HAT domain + inhibitor<br /> | ||
**[[6oin]], [[6oio]], [[6oip]], [[6oir]], [[6owh]], [[6owi]], [[6pd8]], [[6pd9]], [[6pda]], [[6pdb]], [[6pdc]], [[6pdd]], [[6pde]], [[6pdf]], [[6pdg]] – hHAT KAT8 HAT domain (mutant) + inhibitor<br /> | **[[6oin]], [[6oio]], [[6oip]], [[6oir]], [[6owh]], [[6owi]], [[6pd8]], [[6pd9]], [[6pda]], [[6pdb]], [[6pdc]], [[6pdd]], [[6pde]], [[6pdf]], [[6pdg]] – hHAT KAT8 HAT domain (mutant) + inhibitor<br /> | ||
**[[5h86]], [[6ba4]] - hHAT KAT8 HAT domain + acetyl CoA<br /> | **[[5h86]], [[6ba4]] - hHAT KAT8 HAT domain + acetyl CoA<br /> | ||
| - | **[[5ml0]] - | + | **[[7kpy]] - hHAT 617-732 + inhibitor <br /> |
| + | **[[5ml0]] - mHAT KAT2B bromodomain + inhibitor<br /> | ||
**[[1bob]] – yHAT 1 + acetyl-CoA | **[[1bob]] – yHAT 1 + acetyl-CoA | ||
| Line 87: | Line 90: | ||
**[[6vo5]] – hHAT B catalytic subunit + histone H4 + CoA derivative<br /> | **[[6vo5]] – hHAT B catalytic subunit + histone H4 + CoA derivative<br /> | ||
| + | **[[7d0p]], [[7d0q]], [[7d0r]], [[7d0s]] - hHAT KAT7 + BRD1 + CoA derivative<br /> | ||
**[[3q33]] – yHAT RTT109 + vacuolar protein sorting-associated protein 75 + histone H3 peptide<br /> | **[[3q33]] – yHAT RTT109 + vacuolar protein sorting-associated protein 75 + histone H3 peptide<br /> | ||
**[[6o22]] - yHAT RTT109 + vacuolar protein sorting-associated protein 75 + ASF1 + histone H3.2 + histone H4 – NMR<br /> | **[[6o22]] - yHAT RTT109 + vacuolar protein sorting-associated protein 75 + ASF1 + histone H3.2 + histone H4 – NMR<br /> | ||
| Line 111: | Line 115: | ||
**[[5lkz]] - hHAT P300 core (mutant) + crotonyl CoA<br /> | **[[5lkz]] - hHAT P300 core (mutant) + crotonyl CoA<br /> | ||
**[[3biy]] – hHAT P300 acetyltransferase domain + lysine CoA derivative<br /> | **[[3biy]] – hHAT P300 acetyltransferase domain + lysine CoA derivative<br /> | ||
| - | **[[5kj2]] - hHAT P300 acetyltransferase domain + inhibitor<br /> | + | **[[5kj2]], [[7lje]] - hHAT P300 acetyltransferase domain + inhibitor<br /> |
**[[6pf1]], [[6v8b]], [[6v8k]], [[6v8n]], [[6v90]] - hHAT P300 acetyltransferase domain (mutant) + inhibitor<br /> | **[[6pf1]], [[6v8b]], [[6v8k]], [[6v8n]], [[6v90]] - hHAT P300 acetyltransferase domain (mutant) + inhibitor<br /> | ||
**[[6pgu]] - hHAT P300 acetyltransferase domain (mutant) + inhibitor + CoA<br /> | **[[6pgu]] - hHAT P300 acetyltransferase domain (mutant) + inhibitor + CoA<br /> | ||
Revision as of 09:16, 5 September 2021
3D Structures of histone acetyltransferase
Updated on 05-September-2021
