6wfv
From Proteopedia
(Difference between revisions)
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==The crystal structure of a collagen galactosylhydroxylysyl glucosyltransferase from human== | ==The crystal structure of a collagen galactosylhydroxylysyl glucosyltransferase from human== | ||
| - | <StructureSection load='6wfv' size='340' side='right'caption='[[6wfv]]' scene=''> | + | <StructureSection load='6wfv' size='340' side='right'caption='[[6wfv]], [[Resolution|resolution]] 1.70Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WFV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6WFV FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6wfv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WFV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6WFV FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6wfv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wfv OCA], [https://pdbe.org/6wfv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6wfv RCSB], [https://www.ebi.ac.uk/pdbsum/6wfv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6wfv ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr> |
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PLOD3 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6wfv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wfv OCA], [https://pdbe.org/6wfv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6wfv RCSB], [https://www.ebi.ac.uk/pdbsum/6wfv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6wfv ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Disease == | ||
| + | [[https://www.uniprot.org/uniprot/PLOD3_HUMAN PLOD3_HUMAN]] Connective tissue disorder due to lysyl hydroxylase-3 deficiency. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/PLOD3_HUMAN PLOD3_HUMAN]] Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links.[UniProtKB:P24802] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Guo H | + | [[Category: Guo, H F]] |
| - | [[Category: Kurie | + | [[Category: Kurie, J M]] |
| - | [[Category: Miller | + | [[Category: Miller, M D]] |
| - | [[Category: | + | [[Category: Phillips, G N]] |
| - | [[Category: Tainer | + | [[Category: Tainer, J A]] |
| - | [[Category: Tsai C | + | [[Category: Tsai, C L]] |
| + | [[Category: Magnesium]] | ||
| + | [[Category: Manganese]] | ||
| + | [[Category: Rossmann fold]] | ||
| + | [[Category: Transferase]] | ||
| + | [[Category: Udp]] | ||
Revision as of 09:33, 15 September 2021
The crystal structure of a collagen galactosylhydroxylysyl glucosyltransferase from human
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Categories: Human | Large Structures | Guo, H F | Kurie, J M | Miller, M D | Phillips, G N | Tainer, J A | Tsai, C L | Magnesium | Manganese | Rossmann fold | Transferase | Udp
