7o3o
From Proteopedia
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==Structure of haloalkane dehalogenase mutant DhaA80(T148L, G171Q, A172V, C176F) from Rhodococcus rhodochrous with ionic liquid== | ==Structure of haloalkane dehalogenase mutant DhaA80(T148L, G171Q, A172V, C176F) from Rhodococcus rhodochrous with ionic liquid== | ||
| - | <StructureSection load='7o3o' size='340' side='right'caption='[[7o3o]]' scene=''> | + | <StructureSection load='7o3o' size='340' side='right'caption='[[7o3o]], [[Resolution|resolution]] 1.25Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7O3O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7O3O FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7o3o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacterium_mycoides_roseum"_grotenfelt_1889 "bacterium mycoides roseum" grotenfelt 1889]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7O3O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7O3O FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7o3o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7o3o OCA], [https://pdbe.org/7o3o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7o3o RCSB], [https://www.ebi.ac.uk/pdbsum/7o3o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7o3o ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ETA:ETHANOLAMINE'>ETA</scene></td></tr> |
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dhaA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1829 "Bacterium mycoides roseum" Grotenfelt 1889])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Haloalkane_dehalogenase Haloalkane dehalogenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.8.1.5 3.8.1.5] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7o3o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7o3o OCA], [https://pdbe.org/7o3o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7o3o RCSB], [https://www.ebi.ac.uk/pdbsum/7o3o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7o3o ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/DHAA_RHORH DHAA_RHORH]] Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons. Expresses halogenase activity against 1-chloroalkanes of chain length C3 to C10, and also shows a very weak activity with 1,2-dichloroethane. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Bacterium mycoides roseum grotenfelt 1889]] | ||
| + | [[Category: Haloalkane dehalogenase]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Prudnikova, T]] |
| - | [[Category: | + | [[Category: Shaposhnikova, A]] |
| - | [[Category: | + | [[Category: Smatanova, I Kuta]] |
| + | [[Category: Alpha/beta-hydrolase]] | ||
| + | [[Category: Hydrolase]] | ||
Revision as of 09:39, 15 September 2021
Structure of haloalkane dehalogenase mutant DhaA80(T148L, G171Q, A172V, C176F) from Rhodococcus rhodochrous with ionic liquid
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