Interleukin-1 receptor-associated kinase

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Line 20: Line 20:
**[[3mop]] – hIRAK2 DEATH domain + hIRAK4 DEATH domain + MYD88 <br />
**[[3mop]] – hIRAK2 DEATH domain + hIRAK4 DEATH domain + MYD88 <br />
-
*IRAK3
+
*IRAK3; Domains – DEATH 4-106; pseudokinase 145-454
-
**[[5uke]] – hIRAK3 DEATH domain 4-106 (mutant) - NMR<br />
+
**[[5uke]] – hIRAK3 DEATH domain (mutant) - NMR<br />
-
**[[6ziw]] – hIRAK3 residues 141-455 + ATPγS <br />
+
**[[6ziw]] – hIRAK3 pseudokinase domain + ATPgS <br />
 +
**[[6ruu]] – hIRAK3 pseudokinase domain <br />
*IRAK4 kinase domain residues 30-336; DEATH domain residues 4-106
*IRAK4 kinase domain residues 30-336; DEATH domain residues 4-106
Line 30: Line 31:
**[[4u97]], [[4u9a]] - hIRAK4 kinase domain (mutant)<br />
**[[4u97]], [[4u9a]] - hIRAK4 kinase domain (mutant)<br />
**[[2oic]], [[4xs2]] - hIRAK4 kinase domain + staurosporine<br />
**[[2oic]], [[4xs2]] - hIRAK4 kinase domain + staurosporine<br />
-
**[[4y73]], [[4yo6]], [[4yp8]], [[4ztl]], [[4ztm]], [[4ztn]], [[5kx7]], [[5kx8]], [[5t1s]], [[5t1t]], [[5uiq]], [[5uir]], [[5uis]], [[5uit]], [[5uiu]], [[6f3d]], [[6f3e]], [[6f3g]], [[6f3i]], [[6n8g]], [[6o8u]], [[6o94]], [[6o95]], [[6o9d]], [[6uya]], [[6vql]] - hIRAK4 kinase domain + inhibitor<br />
+
**[[4y73]], [[4yo6]], [[4yp8]], [[4ztl]], [[4ztm]], [[4ztn]], [[5kx7]], [[5kx8]], [[5t1s]], [[5t1t]], [[5uiq]], [[5uir]], [[5uis]], [[5uit]], [[5uiu]], [[6f3d]], [[6f3e]], [[6f3g]], [[6f3i]], [[6lxy]], [[6n8g]], [[6o8u]], [[6o94]], [[6o95]], [[6o9d]], [[6thw]], [[6thx]], [[6thz]], [[6ti8]], [[6tia]], [[6uya]], [[6vql]], [[7c2v]], [[7c2w]] - hIRAK4 kinase domain + inhibitor<br />
**[[5w84]], [[5w85]], [[5k72]], [[5k75]], [[5k76]], [[5k7g]], [[5k7i]], [[6ega]], [[6eg9]], [[6egd]], [[6ege]], [[6egf]], [[6mom]], [[6rfi]], [[6rfj]] - hIRAK4 residues 154-460 + inhibitor<br />
**[[5w84]], [[5w85]], [[5k72]], [[5k75]], [[5k76]], [[5k7g]], [[5k7i]], [[6ega]], [[6eg9]], [[6egd]], [[6ege]], [[6egf]], [[6mom]], [[6rfi]], [[6rfj]] - hIRAK4 residues 154-460 + inhibitor<br />
**[[2oid]] - hIRAK4 kinase domain + AMPPNP<br />
**[[2oid]] - hIRAK4 kinase domain + AMPPNP<br />

Revision as of 09:03, 6 October 2021

Mouse IRAK4 death domain complex with Mn+2 ion , 2a9i

Drag the structure with the mouse to rotate

3D structures of interleukin-1 receptor-associated kinase

Updated on 06-October-2021

References

  1. ↑ Cao Z, Henzel WJ, Gao X. IRAK: a kinase associated with the interleukin-1 receptor. Science. 1996 Feb 23;271(5252):1128-31. PMID:8599092

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Jaime Prilusky

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