3hqc
From Proteopedia
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==Crystal structure of Phosphotyrosine-binding domain from the Human Tensin-like C1 domain-containing phosphatase (TENC1)== | ==Crystal structure of Phosphotyrosine-binding domain from the Human Tensin-like C1 domain-containing phosphatase (TENC1)== | ||
| - | <StructureSection load='3hqc' size='340' side='right' caption='[[3hqc]] | + | <StructureSection load='3hqc' size='340' side='right'caption='[[3hqc]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'> | + | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HQC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HQC FirstGlance]. <br> |
| - | </td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hqc OCA], [https://pdbe.org/3hqc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hqc RCSB], [https://www.ebi.ac.uk/pdbsum/3hqc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hqc ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/3hqc TOPSAN]</span></td></tr> |
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| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| - | == Function == | ||
| - | [[http://www.uniprot.org/uniprot/TENC1_HUMAN TENC1_HUMAN]] Regulates cell motility and proliferation. May have phosphatase activity. Reduces AKT1 phosphorylation. Lowers AKT1 kinase activity and interferes with AKT1 signaling.<ref>PMID:15817639</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hqc ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hqc ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| - | == References == | ||
| - | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Atwell | + | [[Category: Atwell S]] |
| - | [[Category: Bain | + | [[Category: Bain K]] |
| - | [[Category: Burley | + | [[Category: Burley SK]] |
| - | [[Category: Dickey | + | [[Category: Dickey M]] |
| - | [[Category: Do | + | [[Category: Do J]] |
| - | [[Category: Gheyi | + | [[Category: Gheyi T]] |
| - | [[Category: Klemke | + | [[Category: Klemke R]] |
| - | + | [[Category: Romero R]] | |
| - | [[Category: Romero | + | [[Category: Sampathkumar P]] |
| - | [[Category: Sampathkumar | + | [[Category: Sauder JM]] |
| - | [[Category: Sauder | + | [[Category: Wasserman S]] |
| - | [[Category: Wasserman | + | |
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Revision as of 12:02, 13 October 2021
Crystal structure of Phosphotyrosine-binding domain from the Human Tensin-like C1 domain-containing phosphatase (TENC1)
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Categories: Large Structures | Atwell S | Bain K | Burley SK | Dickey M | Do J | Gheyi T | Klemke R | Romero R | Sampathkumar P | Sauder JM | Wasserman S
