3kn2
From Proteopedia
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| ==HCV NS3 Protease Domain with ketoamide inhibitor== | ==HCV NS3 Protease Domain with ketoamide inhibitor== | ||
| - | <StructureSection load='3kn2' size='340' side='right' caption='[[3kn2]], [[Resolution|resolution]] 2.30Å' scene=''> | + | <StructureSection load='3kn2' size='340' side='right'caption='[[3kn2]], [[Resolution|resolution]] 2.30Å' scene=''> | 
| == Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3kn2]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3kn2]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepatitis_c_virus_subtype_1a Hepatitis c virus subtype 1a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KN2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KN2 FirstGlance]. <br> | 
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=M66:(1R,2S,5S)-3-{(2S)-2-(2,3-dihydro-1H-inden-2-yl)-2-[({(1S)-2,2-dimethyl-1-[(2-oxopiperidin-1-yl)methyl]propyl}carbamoyl)amino]acetyl}-6,6-dimethyl-N-{(1S)-1-[oxo(prop-2-en-1-ylamino)acetyl]butyl}-3-azabicyclo[3.1.0]hexane-2-carboxamide'>M66</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=M66:(1R,2S,5S)-3-{(2S)-2-(2,3-dihydro-1H-inden-2-yl)-2-[({(1S)-2,2-dimethyl-1-[(2-oxopiperidin-1-yl)methyl]propyl}carbamoyl)amino]acetyl}-6,6-dimethyl-N-{(1S)-1-[oxo(prop-2-en-1-ylamino)acetyl]butyl}-3-azabicyclo[3.1.0]hexane-2-carboxamide'>M66</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | 
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NS3 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NS3 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=31646 Hepatitis C virus subtype 1a])</td></tr> | 
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kn2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kn2 OCA], [https://pdbe.org/3kn2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kn2 RCSB], [https://www.ebi.ac.uk/pdbsum/3kn2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kn2 ProSAT]</span></td></tr> | 
| </table> | </table> | ||
| <div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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| </div> | </div> | ||
| <div class="pdbe-citations 3kn2" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 3kn2" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Virus protease 3D structures|Virus protease 3D structures]] | ||
| == References == | == References == | ||
| <references/> | <references/> | ||
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| </StructureSection> | </StructureSection> | ||
| [[Category: Hepatitis c virus subtype 1a]] | [[Category: Hepatitis c virus subtype 1a]] | ||
| + | [[Category: Large Structures]] | ||
| [[Category: Bogen, S]] | [[Category: Bogen, S]] | ||
| [[Category: Chen, K X]] | [[Category: Chen, K X]] | ||
Revision as of 12:27, 13 October 2021
HCV NS3 Protease Domain with ketoamide inhibitor
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Categories: Hepatitis c virus subtype 1a | Large Structures | Bogen, S | Chen, K X | Nair, L G | Njoroge, G | Pinto, P | Prongay, A | Sannigrahi, M | Atp-binding | Capsid protein | Envelope protein | Helicase | Hepatitis c virus | Host membrane | Hydrolase | Ketoamide inhibitor | Membrane | Ns3 protease domain | Nucleotide-binding | Rna replication | Serine protease | Transmembrane | Virion
