1vr3

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<StructureSection load='1vr3' size='340' side='right'caption='[[1vr3]], [[Resolution|resolution]] 2.06&Aring;' scene=''>
<StructureSection load='1vr3' size='340' side='right'caption='[[1vr3]], [[Resolution|resolution]] 2.06&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1vr3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VR3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VR3 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1vr3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VR3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VR3 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vr3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vr3 OCA], [http://pdbe.org/1vr3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1vr3 RCSB], [http://www.ebi.ac.uk/pdbsum/1vr3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1vr3 ProSAT], [http://www.topsan.org/Proteins/JCSG/1vr3 TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vr3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vr3 OCA], [https://pdbe.org/1vr3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vr3 RCSB], [https://www.ebi.ac.uk/pdbsum/1vr3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vr3 ProSAT], [https://www.topsan.org/Proteins/JCSG/1vr3 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MTND_MOUSE MTND_MOUSE]] Catalyzes the formation of formate and 2-keto-4-methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14 (By similarity).[HAMAP-Rule:MF_03154]
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[[https://www.uniprot.org/uniprot/MTND_MOUSE MTND_MOUSE]] Catalyzes the formation of formate and 2-keto-4-methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14 (By similarity).[HAMAP-Rule:MF_03154]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 13:26, 13 October 2021

Crystal structure of Acireductone dioxygenase (13543033) from Mus musculus at 2.06 A resolution

PDB ID 1vr3

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