Leukocyte-associated immunoglobulin-like receptor

Leukocyte-associated immunoglobulin-like receptors (LAIR-1) is an immunoreceptor tyrosine-based inhibitory motif-bearing receptor expressed in the majority of peripheral mononuclear cells like T cells, B cells and NK cells ^[1].

3D structures of leukocyte-associated immunoglobulin-like receptor

Updated on 17-October-2021

3kgr, 3rp1 – hLAIR-1 ectodomain - human

7f9l, 7f9m, 7f9n – hLAIR-1 ectodomain + rifin
4esk, 4ety – LAIR-1 ectodomain - mouse

References

1. ↑ van der Vuurst de Vries AR, Clevers H, Logtenberg T, Meyaard L. Leukocyte-associated immunoglobulin-like receptor-1 (LAIR-1) is differentially expressed during human B cell differentiation and inhibits B cell receptor-mediated signaling. Eur J Immunol. 1999 Oct;29(10):3160-7. PMID:10540327