3b5i

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==Crystal structure of Indole-3-acetic Acid Methyltransferase==
==Crystal structure of Indole-3-acetic Acid Methyltransferase==
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<StructureSection load='3b5i' size='340' side='right' caption='[[3b5i]], [[Resolution|resolution]] 2.75&Aring;' scene=''>
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<StructureSection load='3b5i' size='340' side='right'caption='[[3b5i]], [[Resolution|resolution]] 2.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3b5i]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B5I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3B5I FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3b5i]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B5I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3B5I FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">IAMT1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">IAMT1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3b5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b5i OCA], [http://pdbe.org/3b5i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3b5i RCSB], [http://www.ebi.ac.uk/pdbsum/3b5i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3b5i ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3b5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b5i OCA], [https://pdbe.org/3b5i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3b5i RCSB], [https://www.ebi.ac.uk/pdbsum/3b5i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3b5i ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/IAMT1_ARATH IAMT1_ARATH]] Catalyzes the methylation of the free carboxyl end of the plant hormone indole-3-acetic acid (IAA). Converts IAA to IAA methyl ester (MeIAA). Regulates IAA activities by IAA methylation. Methylation of IAA plays an important role in regulating plant development and auxin homeostasis. Required for correct leaf pattern formation. MeIAA seems to be an inactive form of IAA.<ref>PMID:12897246</ref> <ref>PMID:16169896</ref> <ref>PMID:17926040</ref>
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[[https://www.uniprot.org/uniprot/IAMT1_ARATH IAMT1_ARATH]] Catalyzes the methylation of the free carboxyl end of the plant hormone indole-3-acetic acid (IAA). Converts IAA to IAA methyl ester (MeIAA). Regulates IAA activities by IAA methylation. Methylation of IAA plays an important role in regulating plant development and auxin homeostasis. Required for correct leaf pattern formation. MeIAA seems to be an inactive form of IAA.<ref>PMID:12897246</ref> <ref>PMID:16169896</ref> <ref>PMID:17926040</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Arath]]
[[Category: Arath]]
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[[Category: Large Structures]]
[[Category: Ferrer, J L]]
[[Category: Ferrer, J L]]
[[Category: Noel, J P]]
[[Category: Noel, J P]]

Revision as of 18:53, 20 October 2021

Crystal structure of Indole-3-acetic Acid Methyltransferase

PDB ID 3b5i

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