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3bt7

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==Structure of E. coli 5-Methyluridine Methyltransferase TrmA in complex with 19 nucleotide T-arm analogue==
==Structure of E. coli 5-Methyluridine Methyltransferase TrmA in complex with 19 nucleotide T-arm analogue==
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<StructureSection load='3bt7' size='340' side='right' caption='[[3bt7]], [[Resolution|resolution]] 2.43&Aring;' scene=''>
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<StructureSection load='3bt7' size='340' side='right'caption='[[3bt7]], [[Resolution|resolution]] 2.43&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3bt7]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BT7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BT7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3bt7]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BT7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BT7 FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=5MU:5-METHYLURIDINE+5-MONOPHOSPHATE'>5MU</scene></td></tr>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=5MU:5-METHYLURIDINE+5-MONOPHOSPHATE'>5MU</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2bh2|2bh2]], [[1uwv|1uwv]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2bh2|2bh2]], [[1uwv|1uwv]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">trmA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">trmA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA_(uracil(54)-C(5))-methyltransferase tRNA (uracil(54)-C(5))-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.35 2.1.1.35] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/tRNA_(uracil(54)-C(5))-methyltransferase tRNA (uracil(54)-C(5))-methyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.35 2.1.1.35] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bt7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bt7 OCA], [http://pdbe.org/3bt7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3bt7 RCSB], [http://www.ebi.ac.uk/pdbsum/3bt7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3bt7 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bt7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bt7 OCA], [https://pdbe.org/3bt7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bt7 RCSB], [https://www.ebi.ac.uk/pdbsum/3bt7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bt7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/TRMA_ECOLI TRMA_ECOLI]] Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs.<ref>PMID:6247318</ref> <ref>PMID:2999071</ref>
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[[https://www.uniprot.org/uniprot/TRMA_ECOLI TRMA_ECOLI]] Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs.<ref>PMID:6247318</ref> <ref>PMID:2999071</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
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*[[TRNA methyltransferase|TRNA methyltransferase]]
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*[[TRNA methyltransferase 3D structures|TRNA methyltransferase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Bacillus coli migula 1895]]
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[[Category: Large Structures]]
[[Category: Alian, A]]
[[Category: Alian, A]]
[[Category: Finer-Moore, J]]
[[Category: Finer-Moore, J]]

Revision as of 19:01, 20 October 2021

Structure of E. coli 5-Methyluridine Methyltransferase TrmA in complex with 19 nucleotide T-arm analogue

PDB ID 3bt7

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