2chw
From Proteopedia
(Difference between revisions)
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<StructureSection load='2chw' size='340' side='right'caption='[[2chw]], [[Resolution|resolution]] 2.60Å' scene=''> | <StructureSection load='2chw' size='340' side='right'caption='[[2chw]], [[Resolution|resolution]] 2.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2chw]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2chw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CHW FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=039:2-((9H-PURIN-6-YLTHIO)METHYL)-5-CHLORO-3-(2-METHOXYPHENYL)QUINAZOLIN-4(3H)-ONE'>039</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=039:2-((9H-PURIN-6-YLTHIO)METHYL)-5-CHLORO-3-(2-METHOXYPHENYL)QUINAZOLIN-4(3H)-ONE'>039</scene></td></tr> |
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1e8y|1e8y]], [[1e8z|1e8z]], [[1he8|1he8]], [[2a4z|2a4z]], [[2a5u|2a5u]], [[2chx|2chx]], [[2chz|2chz]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1e8y|1e8y]], [[1e8z|1e8z]], [[1he8|1he8]], [[2a4z|2a4z]], [[2a5u|2a5u]], [[2chx|2chx]], [[2chz|2chz]]</div></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2chw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2chw OCA], [https://pdbe.org/2chw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2chw RCSB], [https://www.ebi.ac.uk/pdbsum/2chw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2chw ProSAT]</span></td></tr> |
</table> | </table> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
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==See Also== | ==See Also== | ||
| - | *[[Phosphoinositide 3- | + | *[[Phosphoinositide 3-kinase 3D structures|Phosphoinositide 3-kinase 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 20:35, 20 October 2021
A pharmacological map of the PI3-K family defines a role for p110 alpha in signaling: The structure of complex of phosphoinositide 3- kinase gamma with inhibitor PIK-39
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Categories: Human | Large Structures | Balla, A | Balla, T | Feldman, M E | Goldenberg, D D | Gonzalez, B | Knight, Z A | Loewith, R | Shokat, K M | Stokoe, D | Toth, B | Weiss, W A | Williams, O | Williams, R L | Zunder, E R | 3-kinase | Complex transferase-inhibitor | Inhibitor | Kinase | Lipid | Phosphoinositide | Quinazolinone | Signaling | Transferase | Transferase-inhibitor complex | Transferase/inhibitor

