2rs9
From Proteopedia
(Difference between revisions)
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<StructureSection load='2rs9' size='340' side='right'caption='[[2rs9]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | <StructureSection load='2rs9' size='340' side='right'caption='[[2rs9]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[2rs9]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2rs9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RS9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RS9 FirstGlance]. <br> |
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ALY:N(6)-ACETYLLYSINE'>ALY</scene></td></tr> | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ALY:N(6)-ACETYLLYSINE'>ALY</scene></td></tr> | ||
- | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2d9e|2d9e]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2d9e|2d9e]]</div></td></tr> |
- | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BRPF1, BR140 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BRPF1, BR140 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rs9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rs9 OCA], [https://pdbe.org/2rs9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rs9 RCSB], [https://www.ebi.ac.uk/pdbsum/2rs9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rs9 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
- | [[ | + | [[https://www.uniprot.org/uniprot/BRPF1_HUMAN BRPF1_HUMAN]] Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Positively regulates the transcription of RUNX1 and RUNX2.<ref>PMID:16387653</ref> <ref>PMID:18794358</ref> |
==See Also== | ==See Also== |
Revision as of 20:54, 20 October 2021
Solution structure of the bromodomain of human BRPF1 in complex with histone H4K5ac peptide
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Categories: Human | Large Structures | Hayashi, F | Nagashima, T | Qin, X | Structural genomic | Umehara, T | Yokoyama, S | Br140 protein | Bromodomain and phd finger-containing protein 1 | Histone | Human brpf1 protein | National project on protein structural and functional analyse | Nppsfa | Rsgi | Transcription | Transcription activator