1wlz

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<StructureSection load='1wlz' size='340' side='right'caption='[[1wlz]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='1wlz' size='340' side='right'caption='[[1wlz]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1wlz]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WLZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WLZ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1wlz]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WLZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WLZ FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wlz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wlz OCA], [http://pdbe.org/1wlz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1wlz RCSB], [http://www.ebi.ac.uk/pdbsum/1wlz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1wlz ProSAT]</span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wlz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wlz OCA], [https://pdbe.org/1wlz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wlz RCSB], [https://www.ebi.ac.uk/pdbsum/1wlz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wlz ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/EFCB6_HUMAN EFCB6_HUMAN]] Negatively regulates the androgen receptor by recruiting histone deacetylase complex, and protein DJ-1 antagonizes this inhibition by abrogation of this complex.<ref>PMID:12612053</ref>
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[[https://www.uniprot.org/uniprot/EFCB6_HUMAN EFCB6_HUMAN]] Negatively regulates the androgen receptor by recruiting histone deacetylase complex, and protein DJ-1 antagonizes this inhibition by abrogation of this complex.<ref>PMID:12612053</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 16:21, 27 October 2021

Crystal structure of DJBP fragment which was obtained by limited proteolysis

PDB ID 1wlz

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