This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1woy
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='1woy' size='340' side='right'caption='[[1woy]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='1woy' size='340' side='right'caption='[[1woy]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1woy]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1woy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WOY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WOY FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Methionine--tRNA_ligase Methionine--tRNA ligase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.10 6.1.1.10] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1woy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1woy OCA], [https://pdbe.org/1woy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1woy RCSB], [https://www.ebi.ac.uk/pdbsum/1woy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1woy ProSAT], [https://www.topsan.org/Proteins/RSGI/1woy TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/SYM_THET8 SYM_THET8]] Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 16:24, 27 October 2021
Crystal structure of methionyl tRNA synthetase Y225F mutant from Thermus thermophilus
| |||||||||||
Categories: Flavobacterium thermophilum yoshida and oshima 1971 | Large Structures | Methionine--tRNA ligase | Konno, M | Nureki, O | Structural genomic | Takeda, R | Yokoyama, S | Class 1a aminoacyl-trna synthetase | Ligase | Metal-binding | Mutation at tyr225 | National project on protein structural and functional analyse | Nppsfa | Rossmann fold | Rsgi
