1wy5
From Proteopedia
(Difference between revisions)
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<StructureSection load='1wy5' size='340' side='right'caption='[[1wy5]], [[Resolution|resolution]] 2.42Å' scene=''> | <StructureSection load='1wy5' size='340' side='right'caption='[[1wy5]], [[Resolution|resolution]] 2.42Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[1wy5]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1wy5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"aquifex_aeolicus"_huber_and_stetter_2001 "aquifex aeolicus" huber and stetter 2001]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WY5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WY5 FirstGlance]. <br> |
- | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ni5|1ni5]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ni5|1ni5]]</div></td></tr> |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wy5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wy5 OCA], [https://pdbe.org/1wy5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wy5 RCSB], [https://www.ebi.ac.uk/pdbsum/1wy5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wy5 ProSAT], [https://www.topsan.org/Proteins/RSGI/1wy5 TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
- | [[ | + | [[https://www.uniprot.org/uniprot/TILS_AQUAE TILS_AQUAE]] Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity). |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] |
Revision as of 16:30, 27 October 2021
Crystal structure of isoluecyl-tRNA lysidine synthetase
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