User:Luca Paulino Otvos/Sandbox 1
From Proteopedia
| Line 5: | Line 5: | ||
== Function == | == Function == | ||
| - | The protein tyrosine phosphatase localized to the Mitochondrion 1 (PTPMT1) is a dual specificity phosphatases (DUSP) that catalyzes the dephosphorylation of phosphothreonine, phosphoserine and/or phosphotyrosine residues in lipid or protein substrates. Its name came from the fact that it was the first phosphatase identified exclusively in mitochondria <ref>10.1074/jbc.M404959200</ref>. PTPMT1 is a phosphatase directed to the mitochondria by an N-terminal sequence and is found anchored in the inner mitochondrial membrane with its phosphatase domain facing the matrix. | + | The protein tyrosine phosphatase localized to the Mitochondrion 1 (PTPMT1) is a dual specificity phosphatases (DUSP) that catalyzes the dephosphorylation of phosphothreonine, phosphoserine and/or phosphotyrosine residues in lipid or protein substrates. Its name came from the fact that it was the first phosphatase identified exclusively in mitochondria <ref>10.1074/jbc.M404959200</ref>. PTPMT1 is a phosphatase directed to the mitochondria by an N-terminal sequence and is found anchored in the inner mitochondrial membrane with its phosphatase domain facing the matrix <ref>10.1016/j.molcel.2005.06.008<ref>. |
Revision as of 13:15, 1 November 2021
This is a default text for your page Luca Paulino Otvos/Sandbox 1. Click above on edit this page to modify. Be careful with the < and > signs. You may include any references to papers as in: the use of JSmol in Proteopedia [1] or to the article describing Jmol [2] to the rescue.
|
Function
The protein tyrosine phosphatase localized to the Mitochondrion 1 (PTPMT1) is a dual specificity phosphatases (DUSP) that catalyzes the dephosphorylation of phosphothreonine, phosphoserine and/or phosphotyrosine residues in lipid or protein substrates. Its name came from the fact that it was the first phosphatase identified exclusively in mitochondria [3]. PTPMT1 is a phosphatase directed to the mitochondria by an N-terminal sequence and is found anchored in the inner mitochondrial membrane with its phosphatase domain facing the matrix [4]
