7c5p

<StructureSection load='7c5p' size='340' side='right'caption='[[7c5p]], [[Resolution|resolution]] 2.35&Aring;' scene=''>

<table><tr><td colspan='2'>[[7c5p]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecobd Ecobd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7C5P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7C5P FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=G3H:GLYCERALDEHYDE-3-PHOSPHATE'>G3H</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7c5p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7c5p OCA], [https://pdbe.org/7c5p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7c5p RCSB], [https://www.ebi.ac.uk/pdbsum/7c5p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7c5p ProSAT]</span></td></tr>

== Function ==

[[https://www.uniprot.org/uniprot/A0A140NCK4_ECOBD A0A140NCK4_ECOBD]] Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.[ARBA:ARBA00003501]

[[Category: Ecobd]]

[[Category: Bao, L Y]]

[[Category: Bostrom, I K]]

[[Category: Chen, A Q]]

[[Category: Gu, S H]]

[[Category: Ji, C N]]

[[Category: Li, J X]]

[[Category: Liu, M R]]

[[Category: Wang, Y D]]

[[Category: Yao, Y C]]

[[Category: Zhang, L]]

[[Category: Oxidoreductase]]