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1y76
From Proteopedia
(Difference between revisions)
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<StructureSection load='1y76' size='340' side='right'caption='[[1y76]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | <StructureSection load='1y76' size='340' side='right'caption='[[1y76]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1y76]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1y76]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat] and [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y76 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Y76 FirstGlance]. <br> |
| - | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1y74|1y74]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1y74|1y74]]</div></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1y76 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y76 OCA], [https://pdbe.org/1y76 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1y76 RCSB], [https://www.ebi.ac.uk/pdbsum/1y76 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1y76 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/MPDZ_RAT MPDZ_RAT]] Interacts with HTR2C and provokes its clustering at the cell surface. Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses.<ref>PMID:11150294</ref> <ref>PMID:15312654</ref> [[https://www.uniprot.org/uniprot/MPP5_HUMAN MPP5_HUMAN]] May play a role in tight junctions biogenesis and in the establishment of cell polarity in epithelial cells. May modulate SC6A1/GAT1-mediated GABA uptake by stabilizing the transporter. Required for localization of EZR to the apical membrane of parietal cells and may play a role in the dynamic remodeling of the apical cytoskeleton (By similarity). |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 16:24, 3 November 2021
Solution Structure of Patj/Pals1 L27 Domain Complex
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