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1z1x
From Proteopedia
(Difference between revisions)
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<StructureSection load='1z1x' size='340' side='right'caption='[[1z1x]], [[Resolution|resolution]] 3.20Å' scene=''> | <StructureSection load='1z1x' size='340' side='right'caption='[[1z1x]], [[Resolution|resolution]] 3.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1z1x]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1z1x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Echis_carinatus Echis carinatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z1X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z1X FirstGlance]. <br> |
| - | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1rmr|1rmr]], [[1tej|1tej]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1rmr|1rmr]], [[1tej|1tej]]</div></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z1x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z1x OCA], [https://pdbe.org/1z1x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z1x RCSB], [https://www.ebi.ac.uk/pdbsum/1z1x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z1x ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/DID_ECHCA DID_ECHCA]] Inhibits adhesion of cells expressing alpha-4/beta-1 (ITGA4/ITGB1) and alpha-4/beta-7 (ITGA4/ITGB7) integrins to the natural ligands vascular cell adhesion molecule 1 (VCAM-1) and mucosal addressin cell adhesion molecule 1 (MADCAM-1). |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 16:35, 3 November 2021
Crystal Structure of a novel disintegrin from Saw-scaled viper at 3.2 A resolution
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