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1vae

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<StructureSection load='1vae' size='340' side='right'caption='[[1vae]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='1vae' size='340' side='right'caption='[[1vae]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1vae]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VAE OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1VAE FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1vae]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VAE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VAE FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RIKEN cDNA 1300002E07 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RIKEN cDNA 1300002E07 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1vae FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vae OCA], [http://pdbe.org/1vae PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1vae RCSB], [http://www.ebi.ac.uk/pdbsum/1vae PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1vae ProSAT], [http://www.topsan.org/Proteins/RSGI/1vae TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vae FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vae OCA], [https://pdbe.org/1vae PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vae RCSB], [https://www.ebi.ac.uk/pdbsum/1vae PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vae ProSAT], [https://www.topsan.org/Proteins/RSGI/1vae TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RHPN2_MOUSE RHPN2_MOUSE]] Binds specifically to GTP-Rho. May function in a Rho pathway to limit stress fiber formation and/or increase the turnover of F-actin structures in the absence of high levels of RhoA activity (By similarity).
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[[https://www.uniprot.org/uniprot/RHPN2_MOUSE RHPN2_MOUSE]] Binds specifically to GTP-Rho. May function in a Rho pathway to limit stress fiber formation and/or increase the turnover of F-actin structures in the absence of high levels of RhoA activity (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 06:34, 10 November 2021

Solution structure of the PDZ domain of mouse Rhophilin-2

PDB ID 1vae

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