3ehr
From Proteopedia
(Difference between revisions)
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==Crystal Structure of Human Osteoclast Stimulating Factor== | ==Crystal Structure of Human Osteoclast Stimulating Factor== | ||
| - | <StructureSection load='3ehr' size='340' side='right' caption='[[3ehr]], [[Resolution|resolution]] 1.95Å' scene=''> | + | <StructureSection load='3ehr' size='340' side='right'caption='[[3ehr]], [[Resolution|resolution]] 1.95Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3ehr]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3ehr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EHR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EHR FirstGlance]. <br> |
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ehq|3ehq]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3ehq|3ehq]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">OSTF1 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">OSTF1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ehr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ehr OCA], [https://pdbe.org/3ehr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ehr RCSB], [https://www.ebi.ac.uk/pdbsum/3ehr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ehr ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/OSTF1_HUMAN OSTF1_HUMAN]] Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity.<ref>PMID:10092216</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Gao, Y]] | [[Category: Gao, Y]] | ||
[[Category: Niu, L]] | [[Category: Niu, L]] | ||
Revision as of 07:35, 10 November 2021
Crystal Structure of Human Osteoclast Stimulating Factor
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Categories: Human | Large Structures | Gao, Y | Niu, L | Teng, M | Tong, S | Zhang, X | Zhou, H | Zhu, Z | Ank repeat | Ankyrin repeat | Beta barrel | Cytoplasm | Helix-turn-helix | Phosphoprotein | Polymorphism | Sh3 | Sh3 domain | Signaling protein
