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3ezz
From Proteopedia
(Difference between revisions)
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==Crystal Structure of human MKP-2== | ==Crystal Structure of human MKP-2== | ||
| - | <StructureSection load='3ezz' size='340' side='right' caption='[[3ezz]], [[Resolution|resolution]] 2.90Å' scene=''> | + | <StructureSection load='3ezz' size='340' side='right'caption='[[3ezz]], [[Resolution|resolution]] 2.90Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3ezz]] is a 6 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3ezz]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EZZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EZZ FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DUSP4, MKP2, VH2 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DUSP4, MKP2, VH2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ezz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ezz OCA], [https://pdbe.org/3ezz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ezz RCSB], [https://www.ebi.ac.uk/pdbsum/3ezz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ezz ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/DUS4_HUMAN DUS4_HUMAN]] Regulates mitogenic signal transduction by dephosphorylating both Thr and Tyr residues on MAP kinases ERK1 and ERK2. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Jeong, D G]] | [[Category: Jeong, D G]] | ||
[[Category: Jung, S K]] | [[Category: Jung, S K]] | ||
Revision as of 07:37, 10 November 2021
Crystal Structure of human MKP-2
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Categories: Human | Large Structures | Jeong, D G | Jung, S K | Kim, S J | Ryu, S E | Alpha/beta | Hydrolase | Nucleus | Protein phosphatase
