3fbd
From Proteopedia
(Difference between revisions)
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==Crystal structure of the nuclease domain of COLE7(D493Q mutant) in complex with an 18-BP duplex DNA== | ==Crystal structure of the nuclease domain of COLE7(D493Q mutant) in complex with an 18-BP duplex DNA== | ||
| - | <StructureSection load='3fbd' size='340' side='right' caption='[[3fbd]], [[Resolution|resolution]] 2.90Å' scene=''> | + | <StructureSection load='3fbd' size='340' side='right'caption='[[3fbd]], [[Resolution|resolution]] 2.90Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3fbd]] is a 6 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3fbd]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FBD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FBD FirstGlance]. <br> |
| - | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ivh|2ivh]], [[1zns|1zns]], [[1pt3|1pt3]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2ivh|2ivh]], [[1zns|1zns]], [[1pt3|1pt3]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cea, colE7 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cea, colE7 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fbd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fbd OCA], [https://pdbe.org/3fbd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fbd RCSB], [https://www.ebi.ac.uk/pdbsum/3fbd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fbd ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/CEA7_ECOLX CEA7_ECOLX]] This plasmid-coded bactericidal protein is an endonuclease active on both single- and double-stranded DNA but with undefined specificity. Colicins are polypeptide toxins produced by and active against E.coli and closely related bacteria. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
| - | *[[Colicin|Colicin]] | + | *[[Colicin 3D structures|Colicin 3D structures]] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Bacillus coli migula 1895]] | [[Category: Bacillus coli migula 1895]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Doudeva, L G]] | [[Category: Doudeva, L G]] | ||
[[Category: Wang, Y T]] | [[Category: Wang, Y T]] | ||
Revision as of 07:38, 10 November 2021
Crystal structure of the nuclease domain of COLE7(D493Q mutant) in complex with an 18-BP duplex DNA
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Categories: Bacillus coli migula 1895 | Large Structures | Doudeva, L G | Wang, Y T | Yuan, H S | Antibiotic | Antimicrobial | Bacteriocin | Computational redesign | Dna hydrolysis | Dnase | Endonuclease | Hydrolase | Hydrolase-dna complex | Metal-binding | Nuclease | Plasmid | Protein engineering | Protein-nucleic acid interaction | Zinc
