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3gjn
From Proteopedia
(Difference between revisions)
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==Following evolutionary paths to high affinity and selectivity protein-protein interactions using Colicin7 and Immunity proteins== | ==Following evolutionary paths to high affinity and selectivity protein-protein interactions using Colicin7 and Immunity proteins== | ||
| - | <StructureSection load='3gjn' size='340' side='right' caption='[[3gjn]], [[Resolution|resolution]] 2.48Å' scene=''> | + | <StructureSection load='3gjn' size='340' side='right'caption='[[3gjn]], [[Resolution|resolution]] 2.48Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3gjn]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3gjn]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GJN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GJN FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">imm, ceiE9 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">imm, ceiE9 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895]), colE7, cea ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gjn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gjn OCA], [https://pdbe.org/3gjn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gjn RCSB], [https://www.ebi.ac.uk/pdbsum/3gjn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gjn ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/IMM9_ECOLX IMM9_ECOLX]] This protein is able to protect a cell, which harbors the plasmid ColE9 encoding colicin E9, against colicin E9, it binds specifically to the DNase-type colicin and inhibits its bactericidal activity. [[https://www.uniprot.org/uniprot/CEA7_ECOLX CEA7_ECOLX]] This plasmid-coded bactericidal protein is an endonuclease active on both single- and double-stranded DNA but with undefined specificity. Colicins are polypeptide toxins produced by and active against E.coli and closely related bacteria. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
| - | *[[Colicin|Colicin]] | + | *[[Colicin 3D structures|Colicin 3D structures]] |
*[[Colicin Immunity Protein|Colicin Immunity Protein]] | *[[Colicin Immunity Protein|Colicin Immunity Protein]] | ||
| - | *[[ | + | *[[Colicin immunity protein 3D structures|Colicin immunity protein 3D structures]] |
| - | + | ||
| - | + | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Bacillus coli migula 1895]] | [[Category: Bacillus coli migula 1895]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Dym, O]] | [[Category: Dym, O]] | ||
[[Category: Tawfik, D S]] | [[Category: Tawfik, D S]] | ||
Revision as of 07:41, 10 November 2021
Following evolutionary paths to high affinity and selectivity protein-protein interactions using Colicin7 and Immunity proteins
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