3keg
From Proteopedia
(Difference between revisions)
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==X-ray Crystallographic Structure of a Y131F mutant of Pseudomonas Aeruginosa Azoreductase in complex with Methyl RED== | ==X-ray Crystallographic Structure of a Y131F mutant of Pseudomonas Aeruginosa Azoreductase in complex with Methyl RED== | ||
- | <StructureSection load='3keg' size='340' side='right' caption='[[3keg]], [[Resolution|resolution]] 2.10Å' scene=''> | + | <StructureSection load='3keg' size='340' side='right'caption='[[3keg]], [[Resolution|resolution]] 2.10Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[3keg]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3keg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseae Pseae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KEG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KEG FirstGlance]. <br> |
- | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MRE:2-(4-DIMETHYLAMINOPHENYL)DIAZENYLBENZOIC+ACID'>MRE</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MRE:2-(4-DIMETHYLAMINOPHENYL)DIAZENYLBENZOIC+ACID'>MRE</scene></td></tr> |
- | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PA0785 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PA0785 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 PSEAE])</td></tr> |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3keg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3keg OCA], [https://pdbe.org/3keg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3keg RCSB], [https://www.ebi.ac.uk/pdbsum/3keg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3keg ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
- | [[ | + | [[https://www.uniprot.org/uniprot/AZOR1_PSEAE AZOR1_PSEAE]] Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity). |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
+ | [[Category: Large Structures]] | ||
[[Category: Pseae]] | [[Category: Pseae]] | ||
[[Category: Abuhammad, A]] | [[Category: Abuhammad, A]] |
Revision as of 07:50, 10 November 2021
X-ray Crystallographic Structure of a Y131F mutant of Pseudomonas Aeruginosa Azoreductase in complex with Methyl RED
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Categories: Large Structures | Pseae | Abuhammad, A | Laurieri, N | Lowe, E | Ryan, A | Sim, E | Wang, C J | Westwood, I | Flavoprotein | Fmn | Methyl red | Nad | Oxidoreductase | Y131f azoreductase