2l4f
From Proteopedia
(Difference between revisions)
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<StructureSection load='2l4f' size='340' side='right'caption='[[2l4f]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | <StructureSection load='2l4f' size='340' side='right'caption='[[2l4f]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2l4f]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2l4f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L4F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2L4F FirstGlance]. <br> |
| - | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3bq3|3bq3]], [[2l4e|2l4e]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3bq3|3bq3]], [[2l4e|2l4e]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DCN1, DCN1 YLR128W, L3111, YLR128W ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DCN1, DCN1 YLR128W, L3111, YLR128W ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2l4f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l4f OCA], [https://pdbe.org/2l4f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2l4f RCSB], [https://www.ebi.ac.uk/pdbsum/2l4f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2l4f ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/DCN1_YEAST DCN1_YEAST]] Required for neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. Does not act by preventing deneddylation, but rather facilitates neddylation, possibly by acting with HRT1/RBX1 to recruit the Nedd8-charged E2 UBC12 to the cullin component of SCF-type complexes.<ref>PMID:15988528</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 08:33, 10 November 2021
NMR structure of the UBA domain of S. cerevisiae Dcn1 bound to ubiquitin
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