GABAA receptor

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(New page: <StructureSection load='5o8f' size='340' side='right' caption='Structure of a chimaeric beta3-alpha5 GABAA receptor in complex with pregnanolone (based on 5o8f) scene='89/896619/Cv/3'>...)
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<StructureSection load='5o8f' size='340' side='right' caption='Structure of a chimaeric beta3-alpha5 GABAA receptor in complex with pregnanolone (based on [[5o8f]]) scene='89/896619/Cv/3'>
<StructureSection load='5o8f' size='340' side='right' caption='Structure of a chimaeric beta3-alpha5 GABAA receptor in complex with pregnanolone (based on [[5o8f]]) scene='89/896619/Cv/3'>
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This is a default text for your page '''GABAA receptor'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.
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'''GABAA receptors''', which is considered ligand-gated ion channels as the binding of GABA results in the opening of ion channels leading to the inhibition of a neuronal signal. Excitatory neurosteroids have excitatory effects on neurotransmission. They act as potent negative allosteric modulators of the GABAA receptor. Major examples include the pregnanes pregnenolone sulfate (PS), epipregnanolone, and isopregnanolone (sepranolone). *<scene name='89/896619/Cv/5'>Pregnenolone alone</scene>.
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You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.
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*<scene name='89/896619/Cv/4'>Pregnanolone binds beta3-alpha5 GABAA receptor</scene> ([[5o8f]]).
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*<scene name='89/896619/Cv/6'>Pregnanolone binding site is situated between 2 monomers</scene>.
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== Function ==
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== Disease ==
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== Relevance ==
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== Structural highlights ==
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This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
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</StructureSection>
</StructureSection>
== References ==
== References ==
<references/>
<references/>

Revision as of 11:41, 16 November 2021

PDB ID 5o8f

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References

Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Michal Harel

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