Netrin

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*Netrin-1
*Netrin-1
 +
**[[7ne1]] – hNet1 V-VI domains 39-453 + neogenin - human<BR />
 +
**[[7ne0]] – hNet1 V-VI domains + neogenin + RGMB<BR />
 +
**[[7ndg]] – hNet1 V-VI domains + neogenin + RGMB – Cryo EM<BR />
 +
**[[4urt]] – hNet1 V-VI domains + hNet receptor DCC fourth fibronectin type FN5-FN6 domains <BR />
 +
**[[6fkq]] – hNet1 V-VI domains + draxin peptide<BR />
**[[4ove]] – mNet1 – mouse<BR />
**[[4ove]] – mNet1 – mouse<BR />
**[[4plm]] – cNet1 LN-LE3 domains – chicken<BR />
**[[4plm]] – cNet1 LN-LE3 domains – chicken<BR />
**[[4pln]] – cNet1 LN-LE3 domains + neogenin fibronectin type IV-V domains<br />
**[[4pln]] – cNet1 LN-LE3 domains + neogenin fibronectin type IV-V domains<br />
**[[4plo]] – cNet1 LN-LE3 domains + mNet receptor DCC fourth fibronectin type IV-V domains <BR />
**[[4plo]] – cNet1 LN-LE3 domains + mNet receptor DCC fourth fibronectin type IV-V domains <BR />
-
**[[4urt]] – hNet1 LN-LE3 domains + hNet receptor DCC fourth fibronectin type V-VI domains - human<BR />
 
-
**[[6fkq]] – hNet1 LN-LE3 domains + draxin peptide<BR />
 
*Netrin-4
*Netrin-4

Revision as of 10:03, 17 November 2021

Glycosylated mouse netrin-1 complex with Ca+2 and Cl-1 ions (PDB code 4ove)

Drag the structure with the mouse to rotate

3D Structures of netrin

Updated on 17-November-2021

References

  1. Moore SW, Tessier-Lavigne M, Kennedy TE. Netrins and their receptors. Adv Exp Med Biol. 2007;621:17-31. doi: 10.1007/978-0-387-76715-4_2. PMID:18269208 doi:http://dx.doi.org/10.1007/978-0-387-76715-4_2
  2. Ylivinkka I, Hu Y, Chen P, Rantanen V, Hautaniemi S, Nyman TA, Keski-Oja J, Hyytiainen M. Netrin-1-induced activation of Notch signaling mediates glioblastoma cell invasion. J Cell Sci. 2013 Jun 1;126(Pt 11):2459-69. doi: 10.1242/jcs.120022. Epub 2013 Apr, 2. PMID:23549787 doi:http://dx.doi.org/10.1242/jcs.120022
  3. Layne K, Ferro A, Passacquale G. Netrin-1 as a novel therapeutic target in cardiovascular disease: to activate or inhibit? Cardiovasc Res. 2015 Sep 1;107(4):410-9. doi: 10.1093/cvr/cvv201. Epub 2015 Jul, 24. PMID:26209250 doi:http://dx.doi.org/10.1093/cvr/cvv201

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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