6ybh
From Proteopedia
(Difference between revisions)
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==Deoxyribonucleoside Kinase== | ==Deoxyribonucleoside Kinase== | ||
| - | <StructureSection load='6ybh' size='340' side='right'caption='[[6ybh]]' scene=''> | + | <StructureSection load='6ybh' size='340' side='right'caption='[[6ybh]], [[Resolution|resolution]] 2.40Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6YBH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6YBH FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6ybh]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6YBH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6YBH FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ybh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ybh OCA], [https://pdbe.org/6ybh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ybh RCSB], [https://www.ebi.ac.uk/pdbsum/6ybh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ybh ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8LK:Pyrrolo-dC'>8LK</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dnk, CG5452 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Deoxynucleoside_kinase Deoxynucleoside kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.145 2.7.1.145] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ybh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ybh OCA], [https://pdbe.org/6ybh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ybh RCSB], [https://www.ebi.ac.uk/pdbsum/6ybh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ybh ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/DNK_DROME DNK_DROME]] Deoxyribonucleoside kinase that has a broad specificity phosphorylating thymidine, deoxyadenosine, deoxycytidine and deoxyguanosine. Specificity is higher for pyrimidine nucleosides. Several anti-viral and anti-cancer nucleoside analogs are also efficiently phosphorylated.<ref>PMID:10446143</ref> <ref>PMID:10692477</ref> <ref>PMID:16008571</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Deoxynucleoside kinase]] | ||
| + | [[Category: Drome]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Allouche-Arnon H]] | + | [[Category: Allouche-Arnon, H]] |
| - | [[Category: Bar- | + | [[Category: Bar-Shir, A]] |
| - | [[Category: Dym O]] | + | [[Category: Dym, O]] |
| + | [[Category: Transferase]] | ||
Revision as of 14:08, 17 November 2021
Deoxyribonucleoside Kinase
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