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2aim

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<StructureSection load='2aim' size='340' side='right'caption='[[2aim]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='2aim' size='340' side='right'caption='[[2aim]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2aim]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Trycr Trycr]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AIM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AIM FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2aim]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Trycr Trycr]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AIM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AIM FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZRA:BENZOYL-ARGININE-ALANINE-FLUORO-METHYL+KETONE'>ZRA</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZRA:BENZOYL-ARGININE-ALANINE-FLUORO-METHYL+KETONE'>ZRA</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2aim FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aim OCA], [http://pdbe.org/2aim PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2aim RCSB], [http://www.ebi.ac.uk/pdbsum/2aim PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2aim ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2aim FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aim OCA], [https://pdbe.org/2aim PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2aim RCSB], [https://www.ebi.ac.uk/pdbsum/2aim PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2aim ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CYSP_TRYCR CYSP_TRYCR]] Hydrolyzes chromogenic peptides at the carboxyl Arg or Lys; requires at least one more amino acid, preferably Arg, Phe, Val or Leu, between the terminal Arg or Lys and the amino-blocking group. The cysteine protease may play an important role in the development and differentiation of the parasites at several stages of their life cycle.
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[[https://www.uniprot.org/uniprot/CYSP_TRYCR CYSP_TRYCR]] Hydrolyzes chromogenic peptides at the carboxyl Arg or Lys; requires at least one more amino acid, preferably Arg, Phe, Val or Leu, between the terminal Arg or Lys and the amino-blocking group. The cysteine protease may play an important role in the development and differentiation of the parasites at several stages of their life cycle.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 14:41, 17 November 2021

CRUZAIN INHIBITED WITH BENZOYL-ARGININE-ALANINE-FLUOROMETHYLKETONE

PDB ID 2aim

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