2xzz
From Proteopedia
(Difference between revisions)
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<StructureSection load='2xzz' size='340' side='right'caption='[[2xzz]], [[Resolution|resolution]] 2.30Å' scene=''> | <StructureSection load='2xzz' size='340' side='right'caption='[[2xzz]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2xzz]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2xzz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XZZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XZZ FirstGlance]. <br> |
| - | </td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Protein-glutamine_gamma-glutamyltransferase Protein-glutamine gamma-glutamyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.2.13 2.3.2.13] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xzz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xzz OCA], [https://pdbe.org/2xzz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xzz RCSB], [https://www.ebi.ac.uk/pdbsum/2xzz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xzz ProSAT]</span></td></tr> |
</table> | </table> | ||
== Disease == | == Disease == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/TGM1_HUMAN TGM1_HUMAN]] Lamellar ichthyosis;Self-healing collodion baby;Bathing suit ichthyosis;Acral self-healing collodion baby;Congenital non-bullous ichthyosiform erythroderma. The disease is caused by mutations affecting the gene represented in this entry. |
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/TGM1_HUMAN TGM1_HUMAN]] Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Responsible for cross-linking epidermal proteins during formation of the stratum corneum. |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 14:57, 17 November 2021
Crystal structure of the human transglutaminase 1 beta-barrel domain
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