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2bky

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<StructureSection load='2bky' size='340' side='right'caption='[[2bky]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='2bky' size='340' side='right'caption='[[2bky]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2bky]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulso Sulso]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BKY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BKY FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2bky]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Sulso Sulso]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BKY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BKY FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1h0x|1h0x]], [[1h0y|1h0y]], [[1udv|1udv]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1h0x|1h0x]], [[1h0y|1h0y]], [[1udv|1udv]]</div></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bky FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bky OCA], [http://pdbe.org/2bky PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bky RCSB], [http://www.ebi.ac.uk/pdbsum/2bky PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2bky ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bky FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bky OCA], [https://pdbe.org/2bky PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bky RCSB], [https://www.ebi.ac.uk/pdbsum/2bky PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bky ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ALBA1_SULSO ALBA1_SULSO]] Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. May be involved in DNA compaction. May bind rRNA and mRNA, playing a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.[HAMAP-Rule:MF_01122] [[http://www.uniprot.org/uniprot/ALBA2_SULSO ALBA2_SULSO]] Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes (By similarity).
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[[https://www.uniprot.org/uniprot/ALBA1_SULSO ALBA1_SULSO]] Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. May be involved in DNA compaction. May bind rRNA and mRNA, playing a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.[HAMAP-Rule:MF_01122] [[https://www.uniprot.org/uniprot/ALBA2_SULSO ALBA2_SULSO]] Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 13:12, 24 November 2021

Crystal structure of the Alba1:Alba2 heterodimer from sulfolobus solfataricus

PDB ID 2bky

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