7nxf
From Proteopedia
(Difference between revisions)
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==Structure of the fungal plasma membrane proton pump Pma1 in its auto-inhibited state - monomer unit== | ==Structure of the fungal plasma membrane proton pump Pma1 in its auto-inhibited state - monomer unit== | ||
| - | <StructureSection load='7nxf' size='340' side='right'caption='[[7nxf]]' scene=''> | + | <StructureSection load='7nxf' size='340' side='right'caption='[[7nxf]], [[Resolution|resolution]] 3.10Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7NXF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7NXF FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7nxf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Neurospora_crassa Neurospora crassa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7NXF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7NXF FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7nxf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7nxf OCA], [https://pdbe.org/7nxf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7nxf RCSB], [https://www.ebi.ac.uk/pdbsum/7nxf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7nxf ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/P-type_H(+)-exporting_transporter P-type H(+)-exporting transporter], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=7.1.2.1 7.1.2.1] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7nxf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7nxf OCA], [https://pdbe.org/7nxf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7nxf RCSB], [https://www.ebi.ac.uk/pdbsum/7nxf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7nxf ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/A0A0B0DXJ0_NEUCS A0A0B0DXJ0_NEUCS]] The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses.[ARBA:ARBA00003417] | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | [Figure: see text]. | ||
| + | |||
| + | Structure of the hexameric fungal plasma membrane proton pump in its autoinhibited state.,Heit S, Geurts MMG, Murphy BJ, Corey RA, Mills DJ, Kuhlbrandt W, Bublitz M Sci Adv. 2021 Nov 12;7(46):eabj5255. doi: 10.1126/sciadv.abj5255. Epub 2021 Nov, 10. PMID:34757782<ref>PMID:34757782</ref> | ||
| + | |||
| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | <div class="pdbe-citations 7nxf" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Bublitz M]] | + | [[Category: Neurospora crassa]] |
| - | [[Category: Corey R]] | + | [[Category: Bublitz, M]] |
| - | [[Category: Geurts | + | [[Category: Corey, R]] |
| - | [[Category: Heit S]] | + | [[Category: Geurts, M M.G]] |
| - | [[Category: Kuehlbrandt W]] | + | [[Category: Heit, S]] |
| - | [[Category: Mills | + | [[Category: Kuehlbrandt, W]] |
| - | [[Category: Murphy | + | [[Category: Mills, D J]] |
| + | [[Category: Murphy, B J]] | ||
| + | [[Category: Membrane protein]] | ||
| + | [[Category: P-type atpase]] | ||
| + | [[Category: Proton transport]] | ||
| + | [[Category: Proton-transporting atpase]] | ||
Revision as of 06:30, 1 December 2021
Structure of the fungal plasma membrane proton pump Pma1 in its auto-inhibited state - monomer unit
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