7o0o
From Proteopedia
(Difference between revisions)
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==Crystal structure of the B3 metallo-beta-lactamase L1 with hydrolysed ertapenem== | ==Crystal structure of the B3 metallo-beta-lactamase L1 with hydrolysed ertapenem== | ||
| - | <StructureSection load='7o0o' size='340' side='right'caption='[[7o0o]]' scene=''> | + | <StructureSection load='7o0o' size='340' side='right'caption='[[7o0o]], [[Resolution|resolution]] 1.45Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7O0O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7O0O FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7o0o]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7O0O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7O0O FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7o0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7o0o OCA], [https://pdbe.org/7o0o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7o0o RCSB], [https://www.ebi.ac.uk/pdbsum/7o0o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7o0o ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9XS:(2~{S},3~{R},4~{S})-2-[(2~{S},3~{R})-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-[(3~{S},5~{S})-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl]sulfanyl-3-methyl-3,4-dihydro-2~{H}-pyrrole-5-carboxylic+acid'>9XS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7o0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7o0o OCA], [https://pdbe.org/7o0o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7o0o RCSB], [https://www.ebi.ac.uk/pdbsum/7o0o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7o0o ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/BLA1_STEMA BLA1_STEMA]] Has a high activity against imipenem. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Beta-lactamase]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Hinchliffe P]] | + | [[Category: Hinchliffe, P]] |
| - | [[Category: Spencer J]] | + | [[Category: Spencer, J]] |
| + | [[Category: Antibiotic]] | ||
| + | [[Category: Antimicrobial protein]] | ||
| + | [[Category: Carbapenem]] | ||
| + | [[Category: Lactamase]] | ||
| + | [[Category: Ligand]] | ||
| + | [[Category: Metalloprotein]] | ||
Revision as of 06:30, 1 December 2021
Crystal structure of the B3 metallo-beta-lactamase L1 with hydrolysed ertapenem
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