7ryq
From Proteopedia
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==Cryo-EM map of KIFBP== | ==Cryo-EM map of KIFBP== | ||
| - | <StructureSection load='7ryq' size='340' side='right'caption='[[7ryq]]' scene=''> | + | <StructureSection load='7ryq' size='340' side='right'caption='[[7ryq]], [[Resolution|resolution]] 4.60Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RYQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RYQ FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7ryq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RYQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RYQ FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ryq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ryq OCA], [https://pdbe.org/7ryq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ryq RCSB], [https://www.ebi.ac.uk/pdbsum/7ryq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ryq ProSAT]</span></td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">KIFBP, KBP, KIAA1279, KIF1BP ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ryq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ryq OCA], [https://pdbe.org/7ryq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ryq RCSB], [https://www.ebi.ac.uk/pdbsum/7ryq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ryq ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Disease == | ||
| + | [[https://www.uniprot.org/uniprot/KBP_HUMAN KBP_HUMAN]] Goldberg-Shprintzen megacolon syndrome. The disease is caused by variants affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/KBP_HUMAN KBP_HUMAN]] Required for organization of axonal microtubules, and axonal outgrowth and maintenance during peripheral and central nervous system development.<ref>PMID:16225668</ref> <ref>PMID:20621975</ref> <ref>PMID:23427148</ref> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | [Figure: see text]. | ||
| + | |||
| + | Kinesin-binding protein remodels the kinesin motor to prevent microtubule binding.,Solon AL, Tan Z, Schutt KL, Jepsen L, Haynes SE, Nesvizhskii AI, Sept D, Stumpff J, Ohi R, Cianfrocco MA Sci Adv. 2021 Nov 19;7(47):eabj9812. doi: 10.1126/sciadv.abj9812. Epub 2021 Nov, 19. PMID:34797717<ref>PMID:34797717</ref> | ||
| + | |||
| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | <div class="pdbe-citations 7ryq" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Cianfrocco | + | [[Category: Cianfrocco, M A]] |
| - | [[Category: Solon | + | [[Category: Solon, A L]] |
| - | [[Category: Tan Z]] | + | [[Category: Tan, Z]] |
| + | [[Category: Kinesin regulation protein]] | ||
| + | [[Category: Motor protein]] | ||
Revision as of 06:33, 1 December 2021
Cryo-EM map of KIFBP
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