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1ftn

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[[Image:1ftn.jpg|left|200px]]
[[Image:1ftn.jpg|left|200px]]
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{{Structure
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<!--
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|PDB= 1ftn |SIZE=350|CAPTION= <scene name='initialview01'>1ftn</scene>, resolution 2.1&Aring;
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The line below this paragraph, containing "STRUCTURE_1ftn", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=GDP:GUANOSINE-5&#39;-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY=
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or leave the SCENE parameter empty for the default display.
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|GENE= SYNTHETIC HUMAN RHOA GENE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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-->
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|DOMAIN=
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{{STRUCTURE_1ftn| PDB=1ftn | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ftn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ftn OCA], [http://www.ebi.ac.uk/pdbsum/1ftn PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1ftn RCSB]</span>
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}}
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'''CRYSTAL STRUCTURE OF THE HUMAN RHOA/GDP COMPLEX'''
'''CRYSTAL STRUCTURE OF THE HUMAN RHOA/GDP COMPLEX'''
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[[Category: Wei, Y.]]
[[Category: Wei, Y.]]
[[Category: Zhang, Y.]]
[[Category: Zhang, Y.]]
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[[Category: gtp-binding]]
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[[Category: Gtp-binding]]
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[[Category: lipoprotein]]
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[[Category: Lipoprotein]]
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[[Category: prenylation]]
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[[Category: Prenylation]]
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[[Category: proto-oncogene]]
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[[Category: Proto-oncogene]]
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[[Category: small p-protein]]
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[[Category: Small p-protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 16:45:09 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 20:30:08 2008''
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Revision as of 13:45, 2 May 2008

Image:1ftn.jpg

Template:STRUCTURE 1ftn

CRYSTAL STRUCTURE OF THE HUMAN RHOA/GDP COMPLEX


Overview

RhoA, a ubiquitous intracellular GTPase, mediates cytoskeletal responses to extracellular signals. A 2.1 A resolution crystal structure of the human RhoA-GDP complex shows unique stereochemistry in the switch I region, which results in a novel mode of Mg2+ binding.

About this Structure

1FTN is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Crystal structure of RhoA-GDP and its functional implications., Wei Y, Zhang Y, Derewenda U, Liu X, Minor W, Nakamoto RK, Somlyo AV, Somlyo AP, Derewenda ZS, Nat Struct Biol. 1997 Sep;4(9):699-703. PMID:9302995 Page seeded by OCA on Fri May 2 16:45:09 2008

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OCA

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