2cn5
From Proteopedia
(Difference between revisions)
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<StructureSection load='2cn5' size='340' side='right'caption='[[2cn5]], [[Resolution|resolution]] 2.25Å' scene=''> | <StructureSection load='2cn5' size='340' side='right'caption='[[2cn5]], [[Resolution|resolution]] 2.25Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[2cn5]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2cn5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CN5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CN5 FirstGlance]. <br> |
- | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr> |
- | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1gxc|1gxc]], [[2cn8|2cn8]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1gxc|1gxc]], [[2cn8|2cn8]]</div></td></tr> |
- | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cn5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cn5 OCA], [https://pdbe.org/2cn5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cn5 RCSB], [https://www.ebi.ac.uk/pdbsum/2cn5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cn5 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == |
Revision as of 06:58, 1 December 2021
Crystal structure of human Chk2 in complex with ADP
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Categories: Human | Large Structures | Non-specific serine/threonine protein kinase | Oliver, A W | Pearl, L H | Activation segment | Atp-binding | Cancer | Cds1 | Cell cycle | Checkpoint | Chek2 | Chk2 | Disease mutation | Kinase | Kinase domain | Li-fraumeni syndrome | Magnesium | Metal-binding | Nuclear protein | Nucleotide-binding | Phosphorylation | Proto-oncogene | Rad53 | Serine/threonine-protein kinase | Transferase | Tumour suppressor