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2cqx

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<StructureSection load='2cqx' size='340' side='right'caption='[[2cqx]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2cqx' size='340' side='right'caption='[[2cqx]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2cqx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CQX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CQX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2cqx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CQX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CQX FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cqx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cqx OCA], [http://pdbe.org/2cqx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cqx RCSB], [http://www.ebi.ac.uk/pdbsum/2cqx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2cqx ProSAT], [http://www.topsan.org/Proteins/RSGI/2cqx TOPSAN]</span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cqx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cqx OCA], [https://pdbe.org/2cqx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cqx RCSB], [https://www.ebi.ac.uk/pdbsum/2cqx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cqx ProSAT], [https://www.topsan.org/Proteins/RSGI/2cqx TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CERS5_MOUSE CERS5_MOUSE]] Dihydroceramide synthase. Catalyzes the acylation of sphingosine to form dihydroceramide, with high selectivity toward palmitoyl-CoA as acyl donor compared to stearoyl-CoA. Inhibited by fumonisin B1.<ref>PMID:12912983</ref> <ref>PMID:16100120</ref>
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[[https://www.uniprot.org/uniprot/CERS5_MOUSE CERS5_MOUSE]] Dihydroceramide synthase. Catalyzes the acylation of sphingosine to form dihydroceramide, with high selectivity toward palmitoyl-CoA as acyl donor compared to stearoyl-CoA. Inhibited by fumonisin B1.<ref>PMID:12912983</ref> <ref>PMID:16100120</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 06:59, 1 December 2021

Solution structure of RSGI RUH-034, a homeodomain from mouse cDNA

PDB ID 2cqx

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