2kl7
From Proteopedia
(Difference between revisions)
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<StructureSection load='2kl7' size='340' side='right'caption='[[2kl7]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | <StructureSection load='2kl7' size='340' side='right'caption='[[2kl7]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2kl7]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2kl7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KL7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KL7 FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">EFEMP2, FBLN4, UNQ200/PRO226 ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">EFEMP2, FBLN4, UNQ200/PRO226 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kl7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kl7 OCA], [https://pdbe.org/2kl7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kl7 RCSB], [https://www.ebi.ac.uk/pdbsum/2kl7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kl7 ProSAT], [https://www.topsan.org/Proteins/NESGC/2kl7 TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Disease == | == Disease == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/FBLN4_HUMAN FBLN4_HUMAN]] Autosomal recessive cutis laxa type 1;Lethal arteriopathy syndrome due to Fibulin-4 deficiency. The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:16685658</ref> <ref>PMID:17937443</ref> <ref>PMID:19664000</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 07:07, 1 December 2021
Solution NMR Structure of the EGF-like 1 Domain of Human Fibulin-4. Northeast Structural Genomics Target HR6275
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Categories: Human | Large Structures | Anderson, S | Chiang, Y | Montelione, G T | Structural genomic | Rossi, P | Calcium | Disease mutation | Disulfide bond | Egf-like domain | Glycoprotein | Metal binding protein | Nesg | Polymorphism | PSI, Protein structure initiative | Secreted | Signaling protein | Structural protein
