2yt7
From Proteopedia
(Difference between revisions)
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==Solution structure of the PDZ domain of Amyloid beta A4 precursor protein-binding family A member 3== | ==Solution structure of the PDZ domain of Amyloid beta A4 precursor protein-binding family A member 3== | ||
| - | <StructureSection load='2yt7' size='340' side='right' caption='[[2yt7]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | + | <StructureSection load='2yt7' size='340' side='right'caption='[[2yt7]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2yt7]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2yt7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YT7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YT7 FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">APBA3 ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">APBA3 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yt7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yt7 OCA], [https://pdbe.org/2yt7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yt7 RCSB], [https://www.ebi.ac.uk/pdbsum/2yt7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yt7 ProSAT], [https://www.topsan.org/Proteins/RSGI/2yt7 TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/APBA3_HUMAN APBA3_HUMAN]] May modulate processing of the beta-amyloid precursor protein (APP) and hence formation of beta-APP. May enhance the activity of HIF1A in macrophages by inhibiting the activity of HIF1AN.<ref>PMID:19726677</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Dang, W]] | [[Category: Dang, W]] | ||
[[Category: Inoue, M]] | [[Category: Inoue, M]] | ||
Revision as of 07:12, 1 December 2021
Solution structure of the PDZ domain of Amyloid beta A4 precursor protein-binding family A member 3
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Categories: Human | Large Structures | Dang, W | Inoue, M | Kigawa, T | Muto, Y | Structural genomic | Seiki, M | Shirouzu, M | Tarada, T | Yokoyama, S | Adapter protein x11gamma | Amyloid beta a4 precursor protein-binding family a member 3 | Mint-3 | National project on protein structural and functional analyse | Neuron-specific x11l2 protein | Neuronal munc18-1-interacting protein 3 | Nppsfa | Pdz domain | Protein transport | Rsgi
