Outer surface protein
From Proteopedia
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* OspA | * OspA | ||
| - | ** [[2af5]], [[2fkg]], [[2fkj]], [[2hkd]], [[2oyb]] – | + | ** [[2af5]], [[2fkg]], [[2fkj]], [[2hkd]], [[2oyb]], [[6j6b]], [[6j6c]], [[6j6d]], [[6j6e]] – BbOspA – ''Borrelia burgdorferi''<br /> |
** [[2g8c]], [[2i5z]], [[2ol6]], [[2ol7]], [[2ol8]], [[2oy1]], [[2i5v]], [[2oy5]], [[2oy7]], [[2oy8]], [[2pi3]], [[3aum]], [[3cka]], | ** [[2g8c]], [[2i5z]], [[2ol6]], [[2ol7]], [[2ol8]], [[2oy1]], [[2i5v]], [[2oy5]], [[2oy7]], [[2oy8]], [[2pi3]], [[3aum]], [[3cka]], | ||
| - | ** [[3ckf]], [[3ckg]], [[3ec5]], [[3eex]], [[6j49]], [[6j48]], [[5b2a]], [[6j47]], [[5ys7]], [[5z1o]], [[6ais]], [[6ics]], [[6idc]], [[6iei]], [[6iys]], [[6kwj]], [[6kwu]], [[6kwv]] - OspA (mutant) <br /> | + | ** [[3ckf]], [[3ckg]], [[3ec5]], [[3eex]], [[6j49]], [[6j48]], [[5b2a]], [[6j47]], [[5ys7]], [[5z1o]], [[6ais]], [[6ics]], [[6idc]], [[6iei]], [[6iys]], [[6j47]], [[6j48]], [[6j49]], [[6j5m]], [[6j5n]], [[6j5o]], [[6j5p]], [[6j5q]], [[6j5r]], [[6kt1]], [[6ljy]], [[6kk9]], [[6kwj]], [[6kwu]], [[6kwv]] - OspA (mutant) <br /> |
**[[5izt]] – OspA C-terminal<br /> | **[[5izt]] – OspA C-terminal<br /> | ||
| - | ** [[1osp]], [[1fj1]] – OspA (mutant) + antibody<br /> | + | **[[7jwg]] – OspA + antibody<br /> |
| + | **[[1osp]], [[1fj1]] – OspA (mutant) + antibody<br /> | ||
* OspB | * OspB | ||
| - | ** [[2yn7]] – OspB<br /> | + | **[[2yn7]] – OspB<br /> |
| - | ** [[1p4p]] – OspB C terminal<br /> | + | **[[1p4p]] – OspB C terminal<br /> |
| - | ** [[1rjl]] - OspB+ antibody<br /> | + | **[[1rjl]] - OspB+ antibody<br /> |
* OspC | * OspC | ||
| - | ** [[1ggq]], [[1g5z]] – OspC<br /> | + | **[[1ggq]], [[1g5z]], [[7bml]] – OspC<br /> |
| - | ** [[1f1m]] – OspC (mutant) | + | **[[1f1m]] – OspC (mutant)<br /> |
| + | **[[7nen]] – OspC – ''Borrelia garinii''<br /> | ||
* OspE | * OspE | ||
| - | ** [[2m4f]] – OspE – NMR<br /> | + | **[[2m4f]] – OspE – NMR<br /> |
| - | ** [[4j38]] – OspE + complement factor H<br /> | + | **[[4j38]] – OspE + complement factor H<br /> |
**[[5nbq]] – OspE + complement factor H + complement C3<br /> | **[[5nbq]] – OspE + complement factor H + complement C3<br /> | ||
}} | }} | ||
Revision as of 11:07, 1 December 2021
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3D structures of Outer surface proteins (Updated on 01-December-2021)
References
- ↑ Pal U, de Silva AM, Montgomery RR, Fish D, Anguita J, Anderson JF, Lobet Y, Fikrig E. Attachment of Borrelia burgdorferi within Ixodes scapularis mediated by outer surface protein A. J Clin Invest. 2000 Aug;106(4):561-9. PMID:10953031 doi:http://dx.doi.org/10.1172/JCI9427
- ↑ Neelakanta G, Li X, Pal U, Liu X, Beck DS, DePonte K, Fish D, Kantor FS, Fikrig E. Outer surface protein B is critical for Borrelia burgdorferi adherence and survival within Ixodes ticks. PLoS Pathog. 2007 Mar;3(3):e33. PMID:17352535 doi:10.1371/journal.ppat.0030033
- ↑ Carrasco SE, Troxell B, Yang Y, Brandt SL, Li H, Sandusky GE, Condon KW, Serezani CH, Yang XF. Outer surface protein OspC is an antiphagocytic factor that protects Borrelia burgdorferi from phagocytosis by macrophages. Infect Immun. 2015 Dec;83(12):4848-60. doi: 10.1128/IAI.01215-15. Epub 2015 Oct, 5. PMID:26438793 doi:http://dx.doi.org/10.1128/IAI.01215-15
- ↑ Lam TT, Nguyen TP, Montgomery RR, Kantor FS, Fikrig E, Flavell RA. Outer surface proteins E and F of Borrelia burgdorferi, the agent of Lyme disease. Infect Immun. 1994 Jan;62(1):290-8. PMID:8262642
