6kyq
From Proteopedia
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==Crystal structure of DCLK1 Autoinhibited Kinase Domain== | ==Crystal structure of DCLK1 Autoinhibited Kinase Domain== | ||
| - | <StructureSection load='6kyq' size='340' side='right'caption='[[6kyq]]' scene=''> | + | <StructureSection load='6kyq' size='340' side='right'caption='[[6kyq]], [[Resolution|resolution]] 2.14Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KYQ OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[6kyq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KYQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6KYQ FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene></td></tr> |
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DCLK1, DCAMKL1, DCDC3A, KIAA0369 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6kyq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6kyq OCA], [https://pdbe.org/6kyq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6kyq RCSB], [https://www.ebi.ac.uk/pdbsum/6kyq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6kyq ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/DCLK1_HUMAN DCLK1_HUMAN]] Probable kinase that may be involved in a calcium-signaling pathway controlling neuronal migration in the developing brain. May also participate in functions of the mature nervous system. | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Serine/threonine protein kinase 3D structures|Serine/threonine protein kinase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Chen Q]] | + | [[Category: Non-specific serine/threonine protein kinase]] |
| - | [[Category: Yu Y]] | + | [[Category: Chen, Q]] |
| + | [[Category: Yu, Y]] | ||
| + | [[Category: Autoinhibition]] | ||
| + | [[Category: Kinase]] | ||
| + | [[Category: Signaling protein]] | ||
Revision as of 09:58, 8 December 2021
Crystal structure of DCLK1 Autoinhibited Kinase Domain
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