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2d5r
From Proteopedia
(Difference between revisions)
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<StructureSection load='2d5r' size='340' side='right'caption='[[2d5r]], [[Resolution|resolution]] 2.50Å' scene=''> | <StructureSection load='2d5r' size='340' side='right'caption='[[2d5r]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2d5r]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2d5r]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D5R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D5R FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d5r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d5r OCA], [https://pdbe.org/2d5r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d5r RCSB], [https://www.ebi.ac.uk/pdbsum/2d5r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d5r ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/CNOT7_HUMAN CNOT7_HUMAN]] Ubiquitous transcription factor required for a diverse set of processes. It is a component of the CCR4 complex involved in the control of gene expression (By similarity). [[https://www.uniprot.org/uniprot/TOB1_HUMAN TOB1_HUMAN]] Anti-proliferative protein that interacts with the erbB-2 receptor tyrosine kinase. May physically and/or functionally interact with protein-tyrosine kinase receptors. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 10:27, 8 December 2021
Crystal Structure of a Tob-hCaf1 Complex
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