2db7
From Proteopedia
(Difference between revisions)
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<StructureSection load='2db7' size='340' side='right'caption='[[2db7]], [[Resolution|resolution]] 1.90Å' scene=''> | <StructureSection load='2db7' size='340' side='right'caption='[[2db7]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2db7]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2db7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DB7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DB7 FirstGlance]. <br> |
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2db7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2db7 OCA], [https://pdbe.org/2db7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2db7 RCSB], [https://www.ebi.ac.uk/pdbsum/2db7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2db7 ProSAT], [https://www.topsan.org/Proteins/RSGI/2db7 TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/HEY1_HUMAN HEY1_HUMAN]] Downstream effector of Notch signaling which may be required for cardiovascular development. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6.<ref>PMID:11095750</ref> <ref>PMID:15485867</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 10:29, 8 December 2021
Crystal structure of hypothetical protein MS0332
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